Oncogene and miRNA Signaling Pathways as Targets for Cancer Therapeutics

Our lab seeks to understand how specific oncogenes and miRNAs function to drive tumorigenesis.  We are particularly focused on how cancer signaling pathways are activated in breast and liver cancers, amongst the most prevalent and deadly forms of human cancer.  Using a variety of model systems  we seek to develop anti-cancer therapeutics that target the basic cell cycle and may selectively inhibit cancer signaling pathways.