Goga Lab at The University of California, San Francisco

Targeting Oncogene Signaling Pathways For Cancer Therapy

Our lab seeks to understand how specific oncogenes alter the cell cycle, miRNA and metabolic signaling pathways to drive tumorigenesis.  We are particularly focused on how cancer signaling pathways are activated in hematopoietic malignancies, as well as in breast and liver cancers, amongst the most prevalent and deadly forms of human cancer.  Using a variety of model systems  we seek to develop anti-cancer therapeutics to selectively inhibit cancer signaling pathways.